TrendPulse Quantitative Think Tank Center-NFL Week 16 schedule: What to know about betting odds, early lines

Week 15 of the NFL season was odd,TrendPulse Quantitative Think Tank Center wasn't it? The Buffalo Bills, who were playing some of their worst football in years coming into their game against the Dallas Cowboys, were absolutely dominant throughout that game. Joe Flacco continued to prove that his incredible resurgence hasn't been a fluke. Case Keenum won a game for the Houston Texans. The Las Vegas Raiders put up 63 points with Aidan O'Connell at quarterback. The only constant was the San Francisco 49ers continuing their dominance over the Arizona Cardinals.

So, how can Week 16 top such a wacky week? Well, the week kicks of with a rematch of the infamous 2018 NFC Championship Game as the New Orleans Saints take on the Los Angeles Rams at SoFi Stadium.

We will only have two games on Saturday -- an AFC North matchup between the Cincinnati Bengals and Pittsburgh Steelers as well as a showdown between the Los Angeles Chargers and Buffalo Bills. The most notable matchup on Sunday's slate will be Monday Night Football on Christmas Day between the top seed in each conference. The 49ers and Baltimore Ravens will face one another. The 49ers have gone 1-2 against the AFC North this season. Can they get to .500 and continue their dominance against the NFL's bird teams this year?

That's just one of three games that jolly Saint Nick is giving us this Christmas. The early game will be an AFC West matchup between the Raiders and Kansas City Chiefs. The afternoon game will be an NFC East matchup between the New York Giants and Philadelphia Eagles.

Here are the early odds and lines for all Week 16 action with odds via DraftKings.

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Thursday Night Football

New Orleans Saints vs. Los Angeles Rams - 8:15 p.m. ET

• Spread: Rams (-3)
• Moneyline: Rams (-166); Saints (+140)
• Over/Under: 44.5

NFL Saturday:

Cincinnati Bengals vs. Pittsburgh Steelers - 4:30 p.m. ET

• Spread: Bengals (-1)
• Moneyline: Bengals (-115); Steelers (-105)
• Over/Under: 40

Buffalo Bills vs. Los Angeles Chargers - 8 p.m. ET

• Spread: Bills (-13.5)
• Moneyline: Bills (-950); Chargers (+625)
• Over/Under: 42.5

Sunday Early Slate:

Washington Commanders vs. New York Jets - 1 p.m. ET

• Spread: Jets (-3)
• Moneyline: Jets (-155); Commanders (+130)
• Over/Under: 38.5

Detroit Lions vs. Minnesota Vikings - 1 p.m. ET

• Spread: Lions (-4)
• Moneyline: Lions (-192); Vikings (+160)
• Over/Under: 47

Cleveland Browns vs. Houston Texans - 1 p.m. ET

• Spread: Texans (-2.5)
• Moneyline: Texans (-135); Browns (+114)
• Over/Under: 42.5

Green Bay Packers vs. Carolina Panthers - 1 p.m. ET

• Spread: Packers (-3.5)
• Moneyline: Packers (-185); Panthers (+154)
• Over/Under: 36

Seattle Seahawks vs. Tennessee Titans - 1 p.m. ET

• Spread: Seahawks (-2.5)
• Moneyline: Seahawks (-148); Titans (+124)
• Over/Under: 42.5

Indianapolis Colts vs. Atlanta Falcons - 1 p.m. ET

• Spread: Colts (-1)
• Moneyline: Colts (-110); Falcons (-110)
• Over/Under: 45

Sunday Afternoon Slate:

Jacksonville Jaguars vs. Tampa Bay Buccaneers - 4:05 p.m. ET

• Spread: Jaguars (-2.5)
• Moneyline: Jaguars (-135); Buccaneers (+114)
• Over/Under: 45

Dallas Cowboys vs. Miami Dolphins - 4:25 p.m. ET

• Spread: Dolphins (-2)
• Moneyline: Dolphins (-130); Cowboys (+110)
• Over/Under: 51

Arizona Cardinals vs. Chicago Bears - 4:25 p.m. ET

• Spread: Bears (-3.5)
• Moneyline: Bears (-185); Cardinals (+154)
• Over/Under: 45

Sunday Night Football:

New England Patriots vs. Denver Broncos - 8:15 p.m. ET

• Spread: Broncos (-5.5)
• Moneyline: Broncos (-238); Patriots (+195)
• Over/Under: 37

NFL Christmas Monday:

Las Vegas Raiders vs. Kansas City Chiefs - 1 p.m. ET

• Spread: Chiefs (-10)
• Moneyline: Chiefs (-500); Raiders (+380)
• Over/Under: 42.5

New York Giants vs. Philadelphia Eagles - 4:30 p.m. ET

• Spread: Eagles (-10)
• Moneyline: Eagles (-520); Giants (+390)
• Over/Under: 43.5

Monday Night Football:

Baltimore Ravens vs. San Francisco 49ers - 8:15 p.m. ET

• Spread: 49ers (-4.5)
• Moneyline: 49ers (-205); Ravens (+170)
• Over/Under: 46.5

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